DREAM TEAM brings you all the latest injury, suspension and availability news ahead of Gameweek 36 in one easily digestible dose.
Ederson has been ruled out of Manchester City's final Premier League game of the campaign, as well as the FA Cup final, having fractured his eye socket against Tottenham last time out.
Stefan Ortega, who deputised for the Brazilian with aplomb at Spurs, will start at home to West Ham on Sunday and at Wembley the following weekend.
Kevin De Bruyne is due to be assessed after today's training session - the Belgian playmaker took a nasty challenge in midweek but sounded hopeful after the game.
Mikel Arteta's press conference was lacking in team news but Arsenal's tactician previously stated that Bukayo Saka "should be fine" following the winger's substitution against Manchester United.
Man Utd back-up goalkeeper Martin Dubravka recalled by Newcastle
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Nicolo Zaniolo has joined Aston Villa's rather lengthy injury list after fracturing his foot.
Unai Emery won't take any risks with Matty Cash, Youri Tielemans or Morgan Rogers either with the Villains already guaranteed Champions League football next season.
Andy Robertson, Thiago Alcantara and Diogo Jota were all pictured in Liverpool training this week but Jurgen Klopp did not offer updates on the trio's availability.
As for the Reds' opponents, Pedro Neto is expected to be among Wolves' squad at Anfield having returned to training.
Ross Barkley will not feature in what is almost certain to be Luton's last game in the Premier League before relegation is confirmed.
The Hatters' Player of the Season injured his calf last weekend.
Concussion protocols prevent Mykhailo Mudryk from being involved against Bournemouth but Carney Chukwuemeka may take the Ukraine international's place in Chelsea's squad.
Reece James is set to serve the first of his four-game ban having received his second straight red card of the campaign.
Conversely, Milos Kerkez is available for the Cherries following his recent suspension.
How Arsenal could line up against Newcastle with Arteta to name unchanged XI
Eddie Howe was typically vague in his response to a query about Anthony Gordon's condition.
The Newcastle boss said he was "not 100% sure" whether the in-form winger would travel to Brentford this weekend.
After the Magpies' defeat at Old Trafford, Gordon himself said: "I’m not too sure how good my ankle will be."
In more positive news, Callum Wilson is expected to make the matchday squad at the very least - Fabian Schar returned in midweek.
Lewis Dunk is not available for Brighton ahead of Manchester United's visit to the Amex while Tariq Lamptey faces a late fitness test.
ARSENAL
Injuries: Bukayo Saka (doubt)
Suspensions: None
ASTON VILLA
Injuries: Tyrone Mings, Emi Buendia, Boubacar Kamara, Jacob Ramsey, Alex Moreno (doubt), Morgan Rogers, Youri Tielemans, Nicolo Zaniolo, Matty Cash
Suspensions: None
BOURNEMOUTH
Injuries: Ryan Fredericks, Chris Mepham (doubt), Luis Sinisterra, Romain Faivre (doubt)
Suspensions: None
BRENTFORD
Injuries: Aaron Hickey, Rico Henry, Josh Dasilva, Ben Mee, Frank Onyenka (doubt), Nathan Collins (doubt)
Suspensions: None
BRIGHTON
Injuries: Solly March, James Milner, Jack Hinshelwood, Kaoru Mitoma, Evan Ferguson, Tariq Lamptey (doubt), Jan Paul van Hecke, Pervis Estupinan, Lewis Dunk, Joel Veltman (doubt)
Suspensions: None
BURNLEY
Injuries: Luka Koleosho (doubt), Nathan Redmond, Aaron Ramsey, Ameen Al-Dakhil, Jordan Beyer
Suspensions: None
CHELSEA
Injuries: Wesley Fofana, Romeo Lavia, Lesley Ugochukwo (doubt), Robert Sanchez, Enzo Fernandez, Carney Chukwuemeka (doubt), Mykhailo Mudryk
Suspensions: Reece James
CRYSTAL PALACE
Injuries: Cheick Doucoure, Rob Holding, Matheus Franca, Sam Johnstone, Jefferson Lerma (doubt), Will Hughes (doubt)
Suspensions: Naouirou Ahamada
EVERTON
Injuries: Dele Alli, Nathan Patterson, Vitaliy Mykolenko, Jack Harrison, Andre Gomes (doubt)
Suspensions: None
FULHAM
Injuries: Sasa Lukic
Suspensions: Issa Diop
LIVERPOOL
Injuries: Thiago Alcantara (doubt), Ben Doak, Joel Matip, Diogo Jota (doubt), Andy Robertson (doubt)
Suspensions: None
LUTON
Injuries: Tom Lockyer, Marvelous Nakamba, Mads Andersen, Jacob Brown, Amari'i Bell, Dan Potts, Issa Kabore, Ross Barkley
Suspensions: None
MANCHESTER CITY
Injuries: Ederson, Kevin De Bruyne (doubt)
Suspensions: None
MANCHESTER UNITED
Injuries: Tyrell Malacia, Anthony Martial, Luke Shaw, Raphael Varane (doubt), Victor Lindelof (doubt), Mason Mount, Harry Maguire
Suspensions: None
NEWCASTLE
Injuries: Matt Targett, Jamaal Lascelles, Lewis Miley, Sven Botman, Joe Willock, Anthony Gordon (doubt), Tino Livramento
Suspensions: Sandro Tonali
NOTTINGHAM FOREST
Injuries: Neco Williams, Nicolas Dominguez
Suspensions: None
SHEFFIELD UNITED
Injuries: Daniel Jebbison (doubt), John Egan, Chris Basham, Rhys Norrington-Davies, Max Lowe, Rhian Brewster, Tom Davies, George Baldock, Oli McBurnie
Suspensions: None
TOTTENHAM
Injuries: Ryan Sessegnon, Manor Solomon, Fraser Forster, Destiny Udogie, Timo Werner, Ben Davies, Yves Bissouma, Richarlison
Suspensions: None
WEST HAM
Injuries: Nayef Aguerd, Konstantinos Mavropanos, Kalvin Phillips (doubt)
Suspensions: None
WOLVES
Injuries: Criag Dawson, Leon Chwome
Suspensions: None