SUSPECTED human remains have been recovered from the wreckage of the Titan sub, the US Coast Guard confirmed.
All five passengers on the craft, which was destined for the wreck of RMS Titanic, died when it imploded in the North Atlantic.
Brit Hamish Harding, Shahzada Dawood and his son Suleiman Dawood all perished, along with Stockton Rush, the CEO of the company running the trip, and pilot Paul-Henri Nargeolet.
A spokesperson for the Coast Guard said: "United States medical professionals will conduct a formal analysis of presumed human remains that have been carefully recovered within the wreckage at the site of the incident."
Captain Jason Neubauer, chair of the Marine Board of Investigation (MBI), added: "The evidence will provide investigators from several international jurisdictions with critical insights into the cause of this tragedy.
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"There is still a substantial amount of work to be done to understand the factors that led to the catastrophic loss of the TITAN and help ensure a similar tragedy does not occur again."
The five men were the subjects of an international multi-day rescue effort after losing contact with their support ship just an hour and 45 minutes into the dive on June 18.
However, this was tragically found to be in vain as it is believed that the vessel suffered a "catastrophic implosion" when communications dropped out, killing them all instantaneously.
The US Coast Guard will conduct a formal analysis of the "presumed human remains" after transporting the wreckage to a US port.
It comes after the mangled wreckage of the doomed submersible was recovered from the sea floor.
Dr Jasper Graham-Jones, Associate Professor in Mechanical & Marine Engineering at Plymouth University told The Sun investigators will search the salvaged carbon fibre for cracks.
Dr Graham-Jones explained: "Failure investigations start by collecting all available parts. It's critical to make sure you try and collect carefully so that no further damage is caused to collected parts."
However, he added that the process of determining the cause of the implosion could take up to six months.
OceanGate, the company that operated the sub, has faced questions over the safety of the vessel.
One deep-sea explorer claimed that he had pointed out a number of flaws in the craft's design but was alarmed by the "cavalier attitude" taken by staff.
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Likewise, a submarine expert suggested seven clues that the wreck will reveal, including hidden cracks and faulty wiring.
Concerns have included the fact that Titan was steered by a budget video game-style controller and the lack of a GPS system.
It comes after it was revealed that the moment the sub began its ill-fated descent was captured on a video by a crew member.
Meanwhile, the aunt of 19-year-old passenger Suleiman Dawood claimed that he was "terrified" about the trip, but went on it to please his dad, who was a passionate explorer.
Suleiman was studying at Strathclyde University in Glasgow, Scotland, while his father was a successful businessman.
They were accompanied by British billionaire and experienced adventurer Hamish Harding, as well as renowned aviator Rush and Frenchman Nargeolet, who had extensive experience piloting submersibles.
