STEPHEN Fry's "astonishing" weight loss from diabetes jab Ozempic came at a steep price.
The actor and presenter has revealed it left him vomiting multiple times a day.
An "early adopter" of the miracle jab that can make users shed weight by dulling food cravings, the 66-year-old said he was initially amazed by the results.
But Stephen soon had to stop taking the injections, as they left him feeling unwell and being violently sick.
Speaking to the Mirror, he recalled thinking: "I can't do this."
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Ozempic is a once-weekly injection that's prescribed to manage type 2 diabetes.
After it was observed that people taking it also lost weight and had fewer food cravings, the jab's manufacturer Novo Nordisk rolled out a new jab specifically geared towards weight loss, named Wegovy.
Limited supplies of the fat jab were first made available in the UK in September 2023.
Stephen tried said he tried Ozempic "years ago" when he happened to be in the US.
He told the Mirror: "I'd read about it, and I asked my doctor in America, and he said, ‘I think I can get you some'.
"He tried me on it, and the first week or so, I was thinking, ‘This is astonishing. Not only do I not want to eat, I don't want any alcohol of any kind. This is going to be brilliant'."
But the actor's euphoria was short-lived, as he began experiencing grim side effects.
"I started feeling sick, and I started getting sicker and sicker and sicker," he said.
"I was literally throwing up four, five times a day and I thought, ‘I can't do this’. So that's it."
Both Ozempic and Wegovy use the active ingredient semaglutide.
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It works by mimicking a naturally occurring hormone called glucagon-like peptide-1 that's usually released after eating, leading to a reduced appetite and reduced food cravings.
According to Novo Nordisk, common side effects from diabetes drug Ozempic include nausea and vomiting, as well as stomach pain, diarrhoea and constipation.
It advised that you speak to a doctor about side effects, especially if they're bothersome and don't go away.
Studies have found that the trendy fat jabs could put users at higher risk of conditions like of pancreatitis, bowel obstruction and stomach paralysis, even if they were previously healthy.
However, research also shows the fat jabs have potential to treat Alzheimer's and Parkinson's, as well as heart disease, fatty liver disease, and chronic kidney disease.
Speaking to BBC Breakfast in 2019, Stephen said he'd gone on a health kick after his battle with prostate cancer.
At the time, the actor attributed his 5st weight loss and trimmer figure to "lots of walking".
He's not the only celeb to speak openly about his experiences with Ozempic.
Celebrity Big Brother star Sharon Osbourne revealed felt she was "too skinny" after turning to Ozempic weight-loss injections and ditched the jabs, but has been unable to put weight back on.
Meanwhile, a 34-year-old woman revealed she'd experienced "scary" heart palpitations from taking Ozempic.
