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Scientists on the brink of a breakthrough 'cure' for erectile dysfunction

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Scientists on the brink of a breakthrough 'cure' for erectile dysfunction
Scientists on the brink of a breakthrough 'cure' for erectile dysfunction

A BIONIC willy that could restore erectile function has been developed by scientists.

Experiments on pigs found a plastic patch can be used to strengthen tissue that contracts to keep the penis hard when it is erect.

About half of men between the ages of 40 and 70 experience some form of erectile dysfunction eiqriqduiqzxprw
About half of men between the ages of 40 and 70 experience some form of erectile dysfunctionCredit: Getty - Contributor
Illustration of how the sheath work and is placed inside the penis to keep it erect
Illustration of how the sheath work and is placed inside the penis to keep it erectCredit: SWNS

The artificial tunica albuginea (ATA) could help men keep it up, it it also works on humans.

It could repair injuries caused by sex, car and machine accidents, gunshot wounds or burns.

Co-author Dr Xuetao Shi, of the South China University of Technology in Guangzhou, said: "We were still surprised by the results in the animal experiments, where the penis regained normal erection immediately after the use of ATA.

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"The greatest advantage is that it achieves tissue-like functions by mimicking the microstructure of natural tissues."

About half of men between the ages of 40 and 70 experience some form of erectile dysfunction.

About one-in-twenty suffer from Peyronie's disease, a connective tissue disorder that can occur as a result of sex.

Scar tissue forms in the tunica albuginea, causing pain and a range of other effects, explained Dr Shi.

He said: "We noticed that this is an area that has received little attention, yet the related need is huge."

Experts have previously focused on fixing the urethra, a tube that empties the bladder. Patches can treat damaged tunica albuginea tissue.

But this sometimes leads to rejection by the immune system or other complications. The microstructures are different so they are not perfect replacements.

Lab tests showed the device described in the journal Matter is not toxic to other tissues and blood - so can remain in the body for a long time.

In Chinese miniature pigs with injured penises, patches made from the material restored erectile function so well it was similar to that of normal penile tissue.

Results suggest it successfully replaced the natural tissue's function. After a month, ATA developed fibrosis comparable to that in normal tissue.

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They achieved a normal erection after the penis was injected with saline. The animals share anatomical and physiological similarities with humans.

Dr Shi said: "The results one month after the procedure showed the ATA group achieved good, though not perfect, repair results."

In penile injuries the tunica albuginea is usually damaged along with surrounding nerves and the corpus cavernosum.

This is the spongy tissue that runs through the penis' shaft - making repairs even more difficult.

Dr Shi said: "Our work at this stage focuses on the repair of a single tissue in the penis.

"The next stage will be to consider the repair of the overall penile defect or the construction of an artificial penis from a holistic perspective."

The researchers also plan to investigate techniques to repair other tissues - including the heart and bladder.

Dr Shi said: "This design approach is not limited to the biomimetic design of tunica albuginea tissues but can be extended to many other load-bearing tissues."

Isabel Shaw

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